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When an older patient lies obliquely (at an angle) when asked to lie on a bed, he or she may be developing dementia.
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Recurrent peptic ulcer bleeding was increased in patients with known cardiovascular or cerebrovascular disease when daily low-dose aspirin was continued along with proton-pump inhibitors, but overall mortality was significantly less during the 8-week follow-up.
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Low-level lead intoxication, known to adversely affect young children's cognitive development and behavior, may also harm young adults.
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The FDA has approved tranexamic acid, an antifibrinolytic drug, for the treatment of cyclic heavy menstrual bleeding.
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Losartan 150 mg/day reduced left ventricular ejection fraction, intolerance to ACE inhibitors, and the rate of death and/or hospital admission for heart failure in patients with CHF more than did losartan 50 mg/day, thereby demonstrating the potential value of uptitrating ARB doses to confer clinical benefit.
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After 1 year, fewer than half of patients presenting with fatigue will have a diagnosis.
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Fusobacterium necrophorum causes pharyngitis just as often as group A beta-hemolytic streptococcus in adolescents and young adults, and can result in the life-threatening Lemierre's syndrome. Macrolides should be avoided when this pathogen is suspected.
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The FDA has approved capsaicin in a high-concentration, matrix-formulated dermal patch. It is designed to deliver a therapeutic dose into the skin during a 60-minute application. Capsaicin patch is marketed by NeurogesX, Inc., as Qutenza™